Viscoelastic properties of the human tear film.

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dc.contributor.affiliationAston University; University of Milano Bicocca; Birmingham and Midland Eye Centreen_US
dc.contributor.authorRecchioni, Alberto
dc.contributor.authorMocciardini, Emanuele
dc.contributor.authorPonzini, Erika
dc.contributor.authorTavazzi, Silvia
dc.contributor.departmentSandwell and West Birmingham NHS Trusten_US
dc.contributor.roleMedical and Dentalen_US
dc.contributor.trustauthorRecchioni, Alberto
dc.date.accessioned2023-11-27T10:18:53Z
dc.date.available2023-11-27T10:18:53Z
dc.date.issued2022-04-20
dc.description.abstractWhen considering eye blinking from a tribological perspective, tear viscosity is expected to play a fundamental role. The application of rheological techniques to describe the tear film dates back to the late 1980s, but there has been a continuous need of reappraisal due to new findings in tear film biochemistry and to the development of new methods of physico-chemical characterization. This review provides an overview on tear rheological behavior by analyzing the peer-reviewed literature on this topic. Specifically, examples of in-vitro and in-vivo viscosity measurements are detailed, highlighting experimental criticalities and the need of a standard convention for rheological techniques to compare data across different studies, of analyses on tears of single individuals even within the limits of the low volume available, and of a further development of in-vivo techniques. Then, the controversial role of specific tear components on viscosity is discussed, together with the alterations associated to dry eye disease and contact lens wear. Finally, an updated focus is reported on the viscosity of artificial tears formulations.en_US
dc.identifier.citationRecchioni A, Mocciardini E, Ponzini E, Tavazzi S. Viscoelastic properties of the human tear film. Exp Eye Res. 2022 Jun;219:109083.en_US
dc.identifier.doi10.1016/j.exer.2022.109083
dc.identifier.eissn1096-0007
dc.identifier.pmid35460666
dc.identifier.urihttp://hdl.handle.net/20.500.14200/2986
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights
dc.source.beginpage
dc.source.country
dc.source.endpage
dc.source.journaltitleExperimental Eye Research
dc.source.volume
dc.subjectOphthalmologyen_US
dc.titleViscoelastic properties of the human tear film.en_US
dc.typeArticle
dspace.entity.typePublication
oa.grant.openaccessyesen_US
rioxxterms.versionAOen_US
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